Far Cry 4 uses the same engine as the previous game, Dunia Engine 2, albeit updated and modified for the new features GPUs can handle, especially NVIDIA's Gameworks features.  This gives you some idea of how your system will handle the game but for a definitive look at performance just check out this review at [H]ard|OCP.  For their testing they used the GeForce 344.75 WHQL on their GTX 980 and 970 and the Catalyst 14.11.2 Beta for the R9 290X and 290.  On the Ultra preset running at 1440p the performance differences between the AMD and NVIDIA cards were negligible, once they started testing the new features such as the enhanced godrays and AA options there were some significant differences which you should educate yourself about.  It is worth noting that even two GTX 980s in SLI at 3600×1920 are not capable of handling 8x MSAA, thankfully SMAA is supported in the game.

"Far Cry 4 is here, and we take an early look at how current video cards stack up in performance, and which quality settings are graphically demanding. We will also look at some image quality comparisons and talk about the state of this game at launch. Will it measure up to Far Cry 3 in terms of graphic fidelity?"

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