A blog post on NVIDIA's site indicates that Konami's upcoming game Metal Gear Solid 5: The Phantom Pain will make use of NVIDIA technologies, a move that will undoubtedly rankle AMD graphics users who can't always see the full benefit of GameWorks enhancements.
"The world of Metal Gear Solid V: The Phantom Pain is going to be 200 times larger than the one explored in Ground Zeroes. Because so much of this game’s action depends on stealth, graphics are a key part of the gameplay. Shadows, light, and terrain have to be rendered perfectly. That’s a huge challenge in a game where the hero is free to find his own way from one point to another. Our engineers are signed up to work closely with Konami to get the graphics just right and to add special effects."
Now technically this quote doesn't confirm the use of any proprietary NVIDIA technology, though it sounds like that's exactly what will be taking place. In the wake of the Witcher 3 HairWorks controversy any such enhancements will certainly be looked upon with interest (especially as the next piece of big industry news will undoubtedly be coming with AMD's announcement later today at E3).
It's hard to argue with better graphical quality in high profile games such as the latest Metal Gear Solid installment, but there is certainly something to be said for adherence to open standards to ensure a more unified experience across GPUs. The dialog about inclusion though adherence to standards vs. proprietary solutions has been very heated with the FreeSync/G-Sync monitor refresh debate, and GameWorks is a series of tools that serves to further divide gamers, even as it provides an enhanced experience with GeForce GPUs.
Such advantages will likely matter less with DirectX 12 mitigating some differences with more efficiency in the vein of AMD's Mantle API, and if the rumored Fiji cards from AMD offer superior performance and arrive priced competitively this will matter even less. For now even though details are nonexistent expect an NVIDIA GeForce GPU to have the advantage in at least some graphical aspects of the latest Metal Gear title when it arrives on PC.