AMD's recent “Hotfix” drivers don't seem to mean what NVIDIA's does. In the Green Team's case, they usually fix one or two issues that slipped past QA. While they likely won't break anything, they are probably a bad idea to install if you're not experiencing the listed problems. The changelog on AMD's drivers are significantly longer with a list of known issues that is roughly the same size.
So should you install it? That depends. It's a little less cut-and-dry than NVIDIA's hotfixes, which are only useful for a handful of people. It sounds like the worst known issue is “Game stuttering may be experienced when running two Radeon R9 295X2 graphics cards in CrossFire mode” and “Display corruption may occur on multiple display systems when it has been running idle for some time.” The latter would affect me greatly, because I run four displays and basically never sleep or shutdown (except for updates). On the other hand, it fixes a variety of crash, hang, and flicker issues.
Check it out. If it sounds good, then pick it up. Otherwise, wait for the next Beta or WHQL driver.